Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.62 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.62 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25601954 | 0.86 | POLB (0.63) | POLBSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL7932191 | 0.83 | SLC1A3 (0.65) | POLBSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL6329814 | 0.79 | HPGD (0.70) | POLBRAB9ANPC1KMT2AHPGD | |
| SCHEMBL22079053 | 0.76 | RAB9A (0.55) | POLBSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL21765666 | 0.76 | RAB9A (0.71) | POLBSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL21765857 | 0.76 | RAB9A (1.00) | POLBSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL11701768 | 0.75 | RAB9A (0.75) | POLBSLC1A3SLC1A2SLC1A1RAB9A | |
| SCHEMBL23906985 | 0.75 | POLB (0.51) | POLBRAB9ANPC1HPGDMAPT | |
| SCHEMBL2962505 | 0.74 | MAOA (0.84) | POLBRAB9ANPC1CYP1A2ADRA2A | |
| SCHEMBL3984222 | 0.73 | CYP1A2 (0.57) | POLBSLC1A3SLC1A2SLC1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023099922-A1 | INSECT NEUROPEPTIDE ANALOGUES | Solasta Bio Limited (GB) | 2023-06-08 | — | — | WO | disclosed |