Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 15/20 | 0.67 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.67 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.67 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.67 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.67 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.67 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.67 |
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.50 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907376 | 1.00 | LPAR1 (0.67) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23907357 | 0.94 | LPAR1 (0.66) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23907356 | 0.94 | LPAR1 (0.66) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23917596 | 0.93 | LPAR1 (0.57) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23907379 | 0.92 | LPAR1 (0.56) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23917828 | 0.91 | LPAR1 (0.55) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23907359 | 0.90 | LPAR1 (0.65) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL30197677 | 0.90 | LPAR1 (0.65) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23907361 | 0.90 | LPAR1 (0.65) | LPAR1ABCC3ABCC4ABCB11CYP2C8 | |
| SCHEMBL23907381 | 0.89 | LPAR1 (0.51) | LPAR1ABCC3ABCC4ABCB11CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853232-B1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-03-01 | — | — | EP | claimed |
| US-12428430-B2 | Oxabicyclo acids as LPA antagonists | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-09-30 | — | — | US | disclosed |
| EP-3853232-B1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-03-01 | — | — | EP | disclosed |
| US-20210317131-A1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2021-10-14 | — | — | US | disclosed |
| US-20210317131-A1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | BRISTOL-MYERS SQUIBB COMPANY | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12428430-B2 | Oxabicyclo acids as LPA antagonists | LPAR1, LPAR2, LPAR3 | LPAR1 1/4885ABCC3 2680/4885ABCC4 3183/4885 |
| US-20210317131-A1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | LPAR1, LPAR2, LPAR3 | LPAR1 1/4885ABCC3 2680/4885ABCC4 3183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.