Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 16/20 | 0.65 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.65 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.65 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.54 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.54 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23907361 | 1.00 | LPAR1 (0.65) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23907359 | 1.00 | LPAR1 (0.65) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23917828 | 0.92 | LPAR1 (0.55) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23907350 | 0.92 | LPAR1 (0.58) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23907349 | 0.92 | LPAR1 (0.58) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23907375 | 0.90 | LPAR1 (0.67) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23907376 | 0.90 | LPAR1 (0.67) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23917773 | 0.90 | LPAR1 (0.54) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23907366 | 0.89 | LPAR1 (0.58) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL23907365 | 0.89 | LPAR1 (0.58) | LPAR1LPAR3LPAR2ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3853232-B1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-03-01 | — | — | EP | claimed |
| EP-3853232-B1 | OXABICYCLO ACIDS AS LPA ANTAGONISTS | BRISTOL MYERS SQUIBB CO (US) | 2023-03-01 | — | — | EP | disclosed |