Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22187004 | 0.82 | TYR (0.44) | TYRESR1ESR2TP53MAPT | |
| SCHEMBL20680467 | 0.81 | TYR (0.49) | TYRTP53MAPTPOLBMEN1 | |
| SCHEMBL9576130 | 0.78 | TYR (0.39) | TYRESR1ESR2TP53MAPT | |
| SCHEMBL6699498 | 0.78 | TYR (0.39) | TYRESR1ESR2TP53MAPT | |
| SCHEMBL5873065 | 0.78 | TYR (0.43) | TYRESR1ESR2TP53MAPT | |
| SCHEMBL7563496 | 0.78 | TYR (0.43) | TYRESR1ESR2TP53MAPT | |
| SCHEMBL27820066 | 0.78 | TYR (0.49) | TYRESR1ESR2TP53MAPT | |
| SCHEMBL2554417 | 0.78 | ESR1 (0.49) | TYRESR1ESR2AR | |
| SCHEMBL27820125 | 0.78 | TYR (0.45) | TYRESR1ESR2TP53MAPT | |
| SCHEMBL2047429 | 0.78 | ESR1 (0.49) | TYRESR1ESR2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317297-A1 | METHODS AND COMPOSITION OF A DENTAL MODEL FOR THE MANUFACTURE OF ORTHODONTIC APPLIANCES WITHOUT THE USE OF SEPARATOR | STRUCTO PTE LTD (SG) | 2021-10-14 | — | — | US | disclosed |