Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873065 | 1.00 | TYR (0.43) | TYRBCHECYP2C9ESR1ESR2 | |
| SCHEMBL8990202 | 0.93 | BCHE (0.45) | TYRBCHECYP2C9MAPTAMY1A | |
| SCHEMBL5873218 | 0.90 | CYP2C19 (0.40) | TYRBCHECYP2C9ESR1ESR2 | |
| SCHEMBL6650280 | 0.86 | TYR (0.43) | TYRCYP2C9ESR1ESR2CES2 | |
| SCHEMBL6654287 | 0.86 | TYR (0.43) | TYRCYP2C9ESR1ESR2CES2 | |
| SCHEMBL7626442 | 0.83 | PTGS2 (0.51) | TYRESR1TP53HSD17B10HIF1A | |
| SCHEMBL39094 | 0.83 | PTGS2 (0.51) | TYRESR1TP53HSD17B10HIF1A | |
| SCHEMBL27690311 | 0.83 | PTGS2 (0.51) | TYRESR1TP53HSD17B10HIF1A | |
| SCHEMBL8990191 | 0.83 | PTGS2 (0.51) | TYRESR1TP53HSD17B10HIF1A | |
| SCHEMBL3996606 | 0.82 | CYP2C19 (0.44) | TYRCYP2C9ESR1ESR2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020198344-A1 | Stabilized medium and high voltage cable insulation composition | CIBA SPECIALTY CHEMICALS CORP. | 2002-12-26 | — | — | US | disclosed |
| EP-1249845-A2 | Stabilized medium and high voltage cable insulation composition | Ciba SC Holding AG (CH) | 2002-10-16 | — | — | EP | disclosed |