Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL8574712 | 0.97 | TSHR (0.68) | TSHRHTTMEN1THRBKMT2A | |
| Hydrogen Peroxide SCHEMBL28446111 | 0.93 | TSHR (0.72) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL28748446 | 0.93 | TSHR (0.71) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL15167 | 0.93 | — | — | |
| SCHEMBL8600029 | 0.93 | TSHR (0.71) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL439119 | 0.93 | TSHR (0.71) | TSHRHTTMEN1THRBKMT2A | |
| Ethylene Glycol SCHEMBL19739457 | 0.91 | TSHR (0.79) | TSHRHTTMEN1THRBKMT2A | |
| SCHEMBL23581154 | 0.90 | TSHR (0.68) | TSHRHTTMEN1THRBKMT2A | |
| Methyl Alcohol SCHEMBL5708979 | 0.90 | HTT (0.67) | TSHRHTTMEN1THRBKMT2A | |
| Alcohol SCHEMBL2397102 | 0.90 | TSHR (0.78) | TSHRHTTMEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104230031-B | A kind of method extracting multicomponent pharmaceutical and personal-care supplies in surface water | RESEARCH CENTER FOR ECO-ENVIRONMENTAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-16 | — | — | CN | claimed |
| CN-104230031-A | Method for extracting multicomponent drugs and personal care products in surface water | RES CT ECO ENVIRONMENTAL SCIEN | 2014-12-24 | — | — | CN | claimed |
| CN-116116245-A | Method for preparing high-efficiency separation molecular sieve membrane by water-organic solvent heat, high-efficiency separation molecular sieve membrane and application | 安徽工程大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-218130036-U | Energy-saving desulfurizing device for methyl tert-butyl ether | 中国石油化工股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-218130036-U | Energy-saving desulfurizing device for methyl tert-butyl ether | 中国石油化工股份有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-113956269-A | Di (hetero) aryl macrocycles for inhibiting protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2022-01-21 | — | — | CN | disclosed |
| CN-110386944-B | Di (hetero) aryl macrocycles for inhibiting protein kinase activity | 深圳市塔吉瑞生物医药有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-109215827-A | Thermohardening type conductive paste composition and the solar battery cell and solar cell module for having used the composition | 来电子化学股份有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-107109253-A | Process for producing lpg and btx | 沙特基础工业全球技术有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-107074829-A | For suppressing Microsomal prostaglandin E2The new methyl piperidine compound of synthetase 1 | 伊莱利利公司 | 2017-08-18 | — | — | CN | disclosed |
| CN-104230031-B | A kind of method extracting multicomponent pharmaceutical and personal-care supplies in surface water | RESEARCH CENTER FOR ECO-ENVIRONMENTAL SCIENCES, CHINESE ACADEMY OF SCIENCES (CN) | 2016-03-16 | — | — | CN | disclosed |
| CN-102351847-B | Industrial method for refining esomeprazole sodium salt | NANJING YOKO PHARMACEUTICAL CO LTD | 2013-01-23 | — | — | CN | disclosed |
| CN-102351847-A | Industrial method for refining esomeprazole sodium salt | NANJING XINGANG PHARMACEUTICAL CO LTD | 2012-02-15 | — | — | CN | disclosed |
| US-8012980-B2 | Isoquinolinone derivatives | ASTRAZENECA AB (SE) | 2011-09-06 | — | — | US | disclosed |
| CN-101713783-A | Detection kit and detection method of dienestrol | JIANGSU INST OF MICROBIOLOGY C | 2010-05-26 | — | — | CN | disclosed |
| US-20100099665-A1 | ISOQUINOLINONE DERIVATIVES | ASTRAZENECA AB (SE) | 2010-04-22 | — | — | US | disclosed |
| CN-101482562-A | Detection reagent kit and detection method for diethyl stilbestrol | JIANGSU INST OF MICROBIOLOGY C (CN) | 2009-07-15 | — | — | CN | disclosed |
| CN-1024980-C | Non-photographic method for patterning organic polymer films | E I DU PORT DE NEMOURS & CO (US) | 1994-06-08 | — | — | CN | disclosed |
| US-5066658-A | Enzyme Inhibitors; Bronchodilators; Antiinflammatory Agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| CN-1053769-A | Non-photographic patterning process on the organic polymer films | E I DU PORT DE NEMOURS & CO (US) | 1991-08-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099665-A1 | ISOQUINOLINONE DERIVATIVES | SDHA, NQO1, CYP3A5 | TSHR 4083/4885HTT 1233/4885MEN1 3451/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.