SCHEMBL23910893

SCHEMBL23910893

CC(O)c1cc2c(-c3cc(Cl)cc4c3OC(C(=O)N3CCN(C(=O)OC(C)(C)C)CC3)C4)ccnc2n1S(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 12/20 0.46
FNTA P49354 4/20 0.36
FNTB P49356 4/20 0.36
PIK3CA P42336 1/20 0.34
STS P08842 1/20 0.34
TGM2 P21980 2/20 0.33
F13A1 P00488 1/20 0.33
TGM1 P22735 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23911642 0.91 USP7 (0.44) USP7FNTAFNTBPIK3CASTS
SCHEMBL23910820 0.86 USP7 (0.44) USP7FNTAFNTBPIK3CATGM2
SCHEMBL23910648 0.85 USP7 (0.44) USP7FNTAFNTB
SCHEMBL23910843 0.85 USP7 (0.42) USP7FNTAFNTBPIK3CASTS
SCHEMBL23910696 0.85 USP7 (0.43) USP7FNTAFNTB
SCHEMBL23911366 0.83 USP7 (0.45) USP7FNTAFNTBSTSTGM2
SCHEMBL23911432 0.82 USP7 (0.45) USP7FNTAFNTBSTSTGM2
SCHEMBL23910995 0.79 USP7 (0.55) USP7FNTAFNTB
SCHEMBL23911239 0.79 USP7 (0.56) USP7FNTAFNTB
SCHEMBL23911640 0.76 USP7 (0.76) USP7FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 USP7 1/4885FNTA 3267/4885FNTB 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.