SCHEMBL23910905

SCHEMBL23910905

COc1cc(-c2cc(Cl)cc3c2OC(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)C3)ccn1

nearest known ligand 0.58

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 12/20 0.58
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40
TBK1 Q9UHD2 1/20 0.40
GPR119 Q8TDV5 2/20 0.39
CFTR P13569 1/20 0.39
POLB P06746 1/20 0.38
WNT3A P56704 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23911110 0.88 USP7 (0.56) USP7FNTAFNTBGPR119POLB
SCHEMBL23910995 0.81 USP7 (0.55) USP7FNTAFNTBPOLB
SCHEMBL23911640 0.79 USP7 (0.76) USP7FNTAFNTB
SCHEMBL23911355 0.79 USP7 (0.53) USP7FNTAFNTBGPR119
SCHEMBL23910956 0.78 USP7 (0.76) USP7FNTAFNTB
SCHEMBL23911201 0.78 USP7 (0.52) USP7FNTAFNTBPOLB
SCHEMBL23910874 0.78 USP7 (0.51) USP7FNTAFNTBGPR119
SCHEMBL23921707 0.77 USP7 (0.41) USP7FNTAFNTBPOLB
SCHEMBL23911386 0.77 USP7 (0.41) USP7FNTAFNTBPOLB
SCHEMBL23921922 0.75 USP7 (0.80) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 USP7 1/4885FNTA 3267/4885FNTB 1608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.