⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23911072 | 1.00 | — | — | |
| SCHEMBL23911074 | 1.00 | — | — | |
| SCHEMBL23910764 | 0.91 | USP7 (0.32) | — | |
| SCHEMBL23910767 | 0.91 | USP7 (0.32) | — | |
| SCHEMBL23910941 | 0.79 | ESR2 (0.35) | — | |
| SCHEMBL23921728 | 0.79 | ESR2 (0.35) | — | |
| SCHEMBL23911615 | 0.78 | USP7 (0.36) | — | |
| SCHEMBL23911618 | 0.78 | USP7 (0.36) | — | |
| SCHEMBL23910714 | 0.74 | NFKB1 (0.39) | — | |
| SCHEMBL23910670 | 0.74 | NFKB1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317134-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS INC (US) | 2021-10-14 | — | — | US | disclosed |