SCHEMBL23911568

SCHEMBL23911568

O=C(O)N1CCN(C(=O)C2Cc3cc(Cl)cc(-c4ccnc5[nH]c(-c6ccccc6)cc45)c3O2)CC1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
USP7 Q93009 12/20 0.60
KIT P10721 6/20 0.39
AURKA O14965 2/20 0.38
AURKB Q96GD4 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23911093 0.93 USP7 (0.71) USP7KITAURKAAURKB
SCHEMBL23911092 0.93 USP7 (0.71) USP7KITAURKAAURKB
SCHEMBL23911551 0.93 USP7 (0.71) USP7KITAURKAAURKB
SCHEMBL23910700 0.90 USP7 (0.55) USP7KIT
SCHEMBL23910721 0.79 USP7 (0.68) USP7
SCHEMBL23911256 0.79 USP7 (0.68) USP7
SCHEMBL23910724 0.79 USP7 (0.68) USP7
SCHEMBL23921892 0.78 USP7 (0.73) USP7
SCHEMBL23911599 0.78 USP7 (0.73) USP7
SCHEMBL23921895 0.78 USP7 (0.73) USP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF RAPT THERAPEUTICS INC (US) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317134-A1 UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF USP7, SENP7, USP8 USP7 1/4885KIT 2904/4885AURKA 2793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.