Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | CEPT1 | Q9Y6K0 | 1/20 | 0.32 |
| ▸ | CETP | P11597 | 4/20 | 0.31 |
| ▸ | UTRN | P46939 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21553535 | 0.87 | HDAC3 (0.33) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL15858543 | 0.71 | UTRN (0.38) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL29431627 | 0.71 | UTRN (0.38) | HDAC6HDAC3HDAC8HDAC1HDAC2 | |
| SCHEMBL21525986 | 0.71 | UTRN (0.39) | HDAC6MAPTSMN1; SMN2CETPUTRN | |
| SCHEMBL21919762 | 0.71 | CEPT1 (0.32) | HDAC6HDAC3MAPTSMN1; SMN2CEPT1 | |
| SCHEMBL21051271 | 0.70 | UTRN (0.35) | HDAC6MAPTCEPT1UTRNMEN1 | |
| SCHEMBL21810435 | 0.70 | CYP1A2 (0.30) | HDAC6UTRN | |
| SCHEMBL21525980 | 0.70 | CYP1A2 (0.30) | HDAC6UTRN | |
| SCHEMBL20867331 | 0.70 | UTRN (0.32) | MAPTTP53RAB9ASMN1; SMN2UTRN | |
| SCHEMBL18760177 | 0.70 | UTRN (0.35) | HDAC6MAPTCEPT1CETPUTRN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3564238-B1 | FUSED HETEROCYCLIC COMPOUND HAVING OXIME GROUP OR SALTS THEREOF, AGRICULTURAL/HORTICULTURAL INSECTICIDE CONTAINING SAID COMPOUNDS, AND METHOD FOR USING SAID INSECTICIDE | NIHON NOHYAKU CO LTD (JP) | 2021-10-13 | — | — | EP | disclosed |