Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16913970 | 0.87 | GAA (0.49) | HTTTSHRHPGDRAB9AMAPT | |
| SCHEMBL16926917 | 0.87 | GAA (0.53) | TSHRHPGDRAB9AMAPTNPC1 | |
| SCHEMBL16913907 | 0.85 | HPGD (0.54) | TSHRHPGDRAB9AMAPTNPC1 | |
| SCHEMBL3141422 | 0.83 | PIK3C3 (0.54) | HTTTSHRHPGDESR2RAB9A | |
| SCHEMBL3376149 | 0.83 | TSHR (0.51) | HTTTSHRHPGDESR2RAB9A | |
| SCHEMBL16926479 | 0.80 | PIK3C3 (0.53) | CNR2HSP90AA1 | |
| SCHEMBL16996883 | 0.78 | PIK3C3 (0.50) | HPGDESR2HSP90AA1KDM4E | |
| SCHEMBL29717082 | 0.77 | RAB9A (0.57) | HTTHPGDRAB9ACNR1MAPT | |
| SCHEMBL15228320 | 0.75 | HPGD (0.55) | TSHRHPGDESR2RAB9AAKR1C3 | |
| SCHEMBL473906 | 0.74 | KDM4E (0.46) | HPGDAKR1C3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094325-B1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICALS CO (JP) | 2021-10-13 | — | — | EP | disclosed |