Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30426579 | 0.85 | NPC1 (0.56) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL3678013 | 0.85 | NPC1 (0.56) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL8405877 | 0.85 | NPC1 (0.56) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL28344271 | 0.85 | NPC1 (0.56) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL1264655 | 0.84 | NPC1 (0.48) | NPC1RAB9AMAPTSMN1; SMN2MEN1 | |
| SCHEMBL12786267 | 0.77 | KDM4E (0.46) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29256447 | 0.76 | MAPK1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL29040569 | 0.76 | CYP1A2 (0.44) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL28927232 | 0.76 | MAPK1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL28927234 | 0.76 | MAPK1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892615-A1 | PROCESS FOR THE PREPARATION OF SILODOSIN | Minakem (FR) | 2021-10-13 | — | — | EP | disclosed |