Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.31 |
| ▸ | ITGAV | P06756 | 4/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18368272 | 0.90 | NNMT (0.36) | UHRF1NNMTKLKB1MAP4K1PDE3B | |
| SCHEMBL12895015 | 0.86 | UHRF1 (0.42) | UHRF1NNMTKDM4EALDH1A1LMNA | |
| SCHEMBL16195787 | 0.79 | UHRF1 (0.45) | UHRF1NNMTALDH1A1LMNAITGB3 | |
| SCHEMBL5856503 | 0.79 | UHRF1 (0.37) | UHRF1NNMTITGB3ITGAVITGB5 | |
| SCHEMBL20153296 | 0.78 | UHRF1 (0.51) | UHRF1NNMTKDM4EALDH1A1LMNA | |
| SCHEMBL12463306 | 0.77 | ITGAV (0.45) | NNMTITGB3ITGAVITGB5ITGB6 | |
| SCHEMBL5858127 | 0.77 | NNMT (0.38) | UHRF1NNMTITGB3ITGAVITGB5 | |
| SCHEMBL5858119 | 0.77 | NNMT (0.38) | UHRF1NNMTITGB3ITGAVITGB5 | |
| SCHEMBL5858125 | 0.74 | ITGAV (0.34) | UHRF1NNMTKLKB1MAP4K1ITGB3 | |
| SCHEMBL21281647 | 0.73 | UHRF1 (0.42) | UHRF1NNMTITGB3ITGAVITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |