Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 19/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 17/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 17/20 | 0.50 |
| ▸ | ITGB8 | P26012 | 16/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20156314 | 0.86 | ITGB3 (0.65) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL23912858 | 0.82 | ITGB3 (0.67) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL21271425 | 0.78 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL21271426 | 0.78 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL20158388 | 0.77 | ITGAV (0.56) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL23912867 | 0.77 | ITGB3 (0.48) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL21272302 | 0.76 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL21272301 | 0.76 | ITGAV (0.52) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL21272409 | 0.76 | ITGAV (0.50) | ITGAVITGB3ITGB5ITGB6ITGB8 | |
| SCHEMBL21272411 | 0.76 | ITGAV (0.50) | ITGAVITGB3ITGB5ITGB6ITGB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |