Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 20/20 | 0.66 |
| ▸ | ITGB6 | P18564 | 17/20 | 0.66 |
| ▸ | ITGB3 | P05106 | 17/20 | 0.66 |
| ▸ | ITGB8 | P26012 | 16/20 | 0.66 |
| ▸ | ITGB5 | P18084 | 15/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23912919 | 0.88 | ITGB3 (0.63) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL20156075 | 0.88 | ITGB3 (0.65) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL23912906 | 0.77 | ITGAV (0.59) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL23912922 | 0.77 | ITGB3 (0.49) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL21272399 | 0.75 | ITGAV (0.68) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL21272379 | 0.75 | ITGAV (0.68) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL23790348 | 0.74 | ITGAV (0.98) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL23912890 | 0.74 | ITGB3 (0.58) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL20156314 | 0.74 | ITGB3 (0.65) | ITGAVITGB6ITGB3ITGB8ITGB5 | |
| SCHEMBL18029432 | 0.73 | ITGAV (1.00) | ITGAVITGB6ITGB3ITGB8ITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3538527-B1 | AZOLE AMIDES AND AMINES AS ALPHA V INTEGRIN INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2021-10-13 | — | — | EP | disclosed |