⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3089997 | 0.71 | — | — | |
| SCHEMBL29014060 | 0.71 | — | — | |
| SCHEMBL5206816 | 0.66 | — | — | |
| SCHEMBL1408444 | 0.64 | — | — | |
| SCHEMBL24384913 | 0.63 | ALDH1A1 (0.32) | — | |
| SCHEMBL1130420 | 0.62 | — | — | |
| SCHEMBL20427635 | 0.62 | — | — | |
| SCHEMBL1130598 | 0.62 | — | — | |
| SCHEMBL24493682 | 0.62 | — | — | |
| SCHEMBL10049571 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2527435-B2 | Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT 8) gene expression | SANGAMO BIOSCIENCES INC (US) | 2021-10-13 | — | — | EP | disclosed |