Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | SCN4A | P35499 | 6/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18400702 | 0.88 | KDM4E (0.39) | ACHEKDM4EALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL25483059 | 0.85 | ACHE (0.39) | ACHEPKMKDM4EEEDSCN4A | |
| SCHEMBL172240 | 0.84 | ACHE (0.44) | ACHEPKMKDM4EEEDSCN4A | |
| SCHEMBL24122316 | 0.80 | ACHE (0.44) | ACHEPKMKDM4EEEDALDH1A1 | |
| SCHEMBL170719 | 0.77 | ACHE (0.50) | ACHEPKMKDM4EEEDALDH1A1 | |
| SCHEMBL25921571 | 0.75 | TDP1 (0.38) | ACHEPKMKDM4ENR3C1ALDH1A1 | |
| SCHEMBL23269919 | 0.74 | TAAR1 (0.37) | KDM4EALDH1A1SMN1; SMN2KMT2ATAAR1 | |
| SCHEMBL23269529 | 0.74 | TAAR1 (0.37) | KDM4EALDH1A1SMN1; SMN2KMT2ATAAR1 | |
| SCHEMBL170728 | 0.74 | ACHE (0.46) | ACHEPKMKDM4EEEDALDH1A1 | |
| SCHEMBL21612989 | 0.73 | ACHE (0.41) | ACHEPKMKDM4EEEDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892619-A1 | SELECTIVE PI3Ko INHIBITOR AND USE THEREOF | Tarapeutics Science Inc. (CN) | 2021-10-13 | — | — | EP | disclosed |