Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 3/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21786592 | 0.89 | PTGER1 (0.39) | PTGER1CCR5MRGPRX4PLK1MAPT | |
| SCHEMBL22825455 | 0.86 | PTGER1 (0.36) | PTGER1CCR5MRGPRX4PLK1MAPT | |
| SCHEMBL22791092 | 0.86 | PTGER1 (0.35) | PTGER1CCR5MRGPRX4PLK1KMT2A | |
| SCHEMBL24127547 | 0.85 | MAPT (0.39) | PTGER1CCR5MEN1LMNAMAPT | |
| SCHEMBL21786412 | 0.85 | MRGPRX4 (0.40) | PTGER1PTGDR2XDHCCR5MRGPRX4 | |
| SCHEMBL22791325 | 0.83 | PTGDR2 (0.44) | PTGER1PTGDR2XDHCCR5MRGPRX4 | |
| SCHEMBL23913085 | 0.79 | MRGPRX4 (0.40) | PTGER1PTGDR2CCR5MRGPRX4ALOX5 | |
| SCHEMBL22791194 | 0.78 | MRGPRX4 (0.39) | PTGER1XDHMRGPRX4ALOX5ALOX5AP | |
| SCHEMBL19319843 | 0.76 | ALOX5AP (0.42) | PTGER1PTGDR2ALOX5ALOX5APKMT2A | |
| SCHEMBL21786410 | 0.75 | MRGPRX4 (0.41) | PTGER1PTGDR2XDHCCR5MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142504-B2 | Substituted heterocycles as c-MYC targeting agents | NORTHWESTERN UNIVERSITY (US) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142504-B2 | Substituted heterocycles as c-MYC targeting agents | MYC, MYCBP, MYCBP2 | PTGER1 4862/4885PTGDR2 4007/4885XDH 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.