Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913071 | 0.89 | PTGER1 (0.43) | PTGER1MRGPRX4MAPTCCR5RAB9A | |
| SCHEMBL22825455 | 0.89 | PTGER1 (0.36) | PTGER1MRGPRX4HTR2AHTR2CPOLB | |
| SCHEMBL22791092 | 0.88 | PTGER1 (0.35) | PTGER1MRGPRX4HTR2AHTR2CCNR1 | |
| SCHEMBL24127547 | 0.87 | MAPT (0.39) | PTGER1SMN1; SMN2POLBMAPTCCR5 | |
| SCHEMBL21786591 | 0.82 | KMT2A (0.41) | PTGER1FFAR1POLBHPGDMAPT | |
| SCHEMBL22791194 | 0.80 | MRGPRX4 (0.39) | PTGER1MRGPRX4HTR2AHTR2CSMPD1 | |
| SCHEMBL21786411 | 0.77 | KCNT1 (0.36) | PTGER1FFAR1MRGPRX4SMN1; SMN2MAPK1 | |
| SCHEMBL21786529 | 0.76 | PTPN2 (0.39) | PTGER1MRGPRX4KMT2AALDH1A1 | |
| SCHEMBL22791128 | 0.76 | PTGER1 (0.41) | PTGER1MRGPRX4 | |
| SCHEMBL21786627 | 0.76 | MAPT (0.41) | PTGER1FFAR1MRGPRX4MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020046382-A1 | SUBSTITUTED HETEROCYCLES AS C-MYC TARGETING AGENTS | NORTHWESTERN UNIVERSITY (US) | 2020-03-05 | — | — | WO | disclosed |