Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GYS1 | P13807 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21786418 | 0.88 | MRGPRX4 (0.43) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL21786447 | 0.88 | GYS1 (0.39) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL21786408 | 0.88 | HPGD (0.45) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL22790944 | 0.86 | SMPD1 (0.39) | GYS1NPSR1ALOX5APTP53MAPK1 | |
| SCHEMBL22791321 | 0.86 | GYS1 (0.38) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL21786417 | 0.86 | ALOX5AP (0.37) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL23913081 | 0.85 | GYS1 (0.41) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL21786588 | 0.85 | MRGPRX4 (0.39) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL21786628 | 0.84 | SLC6A4 (0.40) | GYS1NPSR1MAPTL3MBTL1ALOX5AP | |
| SCHEMBL21786469 | 0.84 | SLC6A4 (0.40) | GYS1NPSR1MAPTL3MBTL1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142504-B2 | Substituted heterocycles as c-MYC targeting agents | NORTHWESTERN UNIVERSITY (US) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142504-B2 | Substituted heterocycles as c-MYC targeting agents | MYC, MYCBP, MYCBP2 | GYS1 4422/4885NPSR1 4023/4885MAPT 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.