SCHEMBL239131

SCHEMBL239131

NC(N)=C(N)CCCCCC(N)=C(N)N

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SPHK2 Q9NRA0 1/20 0.35
SPHK1 Q9NYA1 1/20 0.35
LMNA P02545 2/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
PMP22 Q01453 1/20 0.32
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
PLG P00747 1/20 0.30
THRB P10828 1/20 0.30
ALOX15 P16050 1/20 0.30
SLC6A2 P23975 1/20 0.30
RECQL P46063 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23358989 0.85 SPHK2 (0.56) SPHK2SPHK1TSHRMEN1ALDH1A1
SCHEMBL7718829 0.85 SPHK2 (0.56) SPHK2SPHK1TSHRMEN1ALDH1A1
SCHEMBL1531606 0.85 SPHK2 (0.56) SPHK2SPHK1TSHRMEN1ALDH1A1
SCHEMBL23358828 0.85 SPHK2 (0.56) SPHK2SPHK1TSHRMEN1ALDH1A1
SCHEMBL11154561 0.85 SPHK2 (0.56) SPHK2SPHK1TSHRMEN1ALDH1A1
SCHEMBL23358970 0.81 SPHK2 (0.52) SPHK2SPHK1TSHRMEN1ALDH1A1
SCHEMBL10702830 0.76
SCHEMBL11206468 0.67 PAOX (0.33) SPHK2SPHK1
SCHEMBL25293705 0.64 KMT2A (0.52) LMNATSHRNFKB1PMP22MEN1
SCHEMBL727151 0.64 KMT2A (0.52) LMNATSHRNFKB1PMP22MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12291600-B2 Three-dimensional spherical alpha-helix cationic polypeptide having high-efficiency gene delivery capability, and preparation method and application thereof SOOCHOW UNIVERSITY (CN) 2025-05-06 US claimed
WO-2025076244-A1 MOISTURE CURABLE ACRYLIC POLYMER COMPOSITIONS BASF SE (DE) 2025-04-10 WO claimed
US-20230094088-A1 THREE-DIMENSIONAL SPHERICAL ALPHA-HELIX CATIONIC POLYPEPTIDE HAVING HIGH-EFFICIENCY GENE DELIVERY CAPABILITY, AND PREPARATION METHOD AND APPLICATION THEREOF SOOCHOW UNIVERSITY (CN) 2023-03-30 US claimed
CN-112449646-A Polyurethane foam having excellent flame resistance and process for producing the same 韩国卡奔株式会社 2021-03-05 CN claimed
CN-111560108-A Full-water polyurethane rigid foam and preparation method and application thereof 上海抚佳精细化工有限公司 2020-08-21 CN claimed
CN-111533874-A Polyurethane high-resilience foam and preparation method thereof 上海抚佳精细化工有限公司 2020-08-14 CN claimed
EP-0949285-B1 Process for manufacturing polyurethane foam BASF AG (DE) 2002-06-12 EP claimed
US-4902736-A COMPONENT WITH SILYLTHIO ETHER GROUPS AND POLYESTHERURETHANE OR POLYETHERURETHANE COPOLYMER;FREE OF CARBON DIOXIDE; HEAT RESISTANCE TORAY THIOKOL COMPANY LIMITED (JP) 1990-02-20 US claimed
JP-63295617-A None JP disclosed
US-20250346711-A1 COPOLYMER, ELASTOMER SPHERICAL PARTICLES, LIQUID DISPERSION OF ELASTOMER SPHERICAL PARTICLES, AND METHODS FOR PRODUCING THESE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-11-13 US disclosed
US-20250129227-A1 A REACTION MIXTURE FOR MANUFACTURING AN INORGANIC-FILLER BASED CLOSED-CELL RIGID PIR-COMPRISING FOAM HUNTSMAN INTERNATIONAL LLC 2025-04-24 US disclosed
WO-2025076244-A1 MOISTURE CURABLE ACRYLIC POLYMER COMPOSITIONS BASF SE (DE) 2025-04-10 WO disclosed
EP-4530303-A1 COPOLYMER, ELASTOMER SPHERICAL PARTICLES, LIQUID DISPERSION OF ELASTOMER SPHERICAL PARTICLES, AND METHODS FOR PRODUCING THESE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-04-02 EP disclosed
US-20250101198-A1 A REACTION MIXTURE FOR MANUFACTURING AN INORGANIC-FILLER BASED CLOSED-CELL RIGID POLYURETHANE OR POLYISOCYANURATE CONTAINING FOAM WITH LOW WATER CONTENT HUNTSMAN INTERNATIONAL LLC 2025-03-27 US disclosed
US-5576558-A Primer composition containing polyisocyanate and phosphate for bonding to a hard-to-bond material THE YOKOHAMA RUBBER CO., LTD. (JP) 1996-11-19 US disclosed
US-5319057-A A copolymer of polyetherurethane with polysulfide/polymer/ or polythioethers; foamless, weatherproofing, noncracking TORAY THIOKOL CO., LTD. (JP) 1994-06-07 US disclosed
EP-0295307-B1 ONE-PACK CURING COMPOSITION TORAY THIOKOL COMPANY LIMITED (JP) 1992-03-25 EP disclosed
US-4902736-A COMPONENT WITH SILYLTHIO ETHER GROUPS AND POLYESTHERURETHANE OR POLYETHERURETHANE COPOLYMER;FREE OF CARBON DIOXIDE; HEAT RESISTANCE TORAY THIOKOL COMPANY LIMITED (JP) 1990-02-20 US disclosed
EP-0295307-A1 ONE-PACK CURING COMPOSITION TORAY THIOKOL COMPANY LIMITED (JP) 1988-12-21 EP disclosed
JP-S63295617-A PRODUCTION OF RIGID HEAT-INSULATING URETHANE FOAM TOSHIBA CORP 1988-12-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230094088-A1 THREE-DIMENSIONAL SPHERICAL ALPHA-HELIX CATIONIC POLYPEPTIDE HAVING HIGH-EFFICIENCY GENE DELIVERY CAPABILITY, AND PREPARATION METHOD AND APPLICATION THEREOF SCAMP3, GPKOW, SLC7A1 SPHK2 2192/4885SPHK1 2570/4885LMNA 530/4885
US-12291600-B2 Three-dimensional spherical alpha-helix cationic polypeptide having high-efficiency gene delivery capability, and preparation method and application thereof SCAMP3, GPKOW, SLC7A1 SPHK2 2192/4885SPHK1 2570/4885LMNA 530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.