Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25973926 | 0.86 | MCL1 (0.40) | MCL1TSHRPDE2AARESR1 | |
| SCHEMBL171040 | 0.84 | PDE2A (0.50) | HSD11B1MCL1TSHRPDE2AALDH1A1 | |
| SCHEMBL9912479 | 0.81 | TSHR (0.46) | HSD11B1MCL1TSHRESR1CD44 | |
| SCHEMBL3950702 | 0.81 | ESR1 (0.54) | MCL1TSHRARESR1CD44 | |
| SCHEMBL3956006 | 0.80 | ESR1 (0.41) | MCL1TSHRPDE2AARESR1 | |
| SCHEMBL5355972 | 0.80 | TSHR (0.37) | MCL1TSHRPDE2AARRAPGEF4 | |
| SCHEMBL27416926 | 0.79 | MCL1 (0.36) | MCL1TSHRPDE2AARESR1 | |
| SCHEMBL29051999 | 0.79 | MCL1 (0.36) | HSD11B1MCL1TSHRPDE2AAR | |
| SCHEMBL23592890 | 0.78 | ALDH1A1 (0.40) | HSD11B1TSHRPDE2AARESR1 | |
| SCHEMBL2277025 | 0.77 | PDE2A (0.43) | MCL1TSHRPDE2AESR1CD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892618-A1 | 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |