SCHEMBL23914472

SCHEMBL23914472

COc1cc(C(=O)OCCC(=O)OC(C)(C)C)cc(OC)c1OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC29A1 Q99808 6/20 0.56
SCN1A P35498 2/20 0.54
SCN2A Q99250 2/20 0.54
SCN3A Q9NY46 2/20 0.54
CYP3A4 P08684 2/20 0.51
CYP2D6 P10635 2/20 0.51
THPO P40225 2/20 0.51
MTOR P42345 2/20 0.51
KMT2A Q03164 6/20 0.50
MEN1 O00255 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
LMNA P02545 2/20 0.50
PMP22 Q01453 2/20 0.50
TSHR P16473 2/20 0.50
ABCC4 O15439 1/20 0.50
CYP2C9 P11712 1/20 0.50
CHRM3 P20309 1/20 0.50
HTR2A P28223 1/20 0.50
MAPK1 P28482 1/20 0.50
SLC6A4 P31645 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23913855 0.86 SMN1; SMN2 (0.56) SLC29A1SCN1ASCN2ASCN3ACYP3A4
SCHEMBL23914471 0.78 SERPINE1 (0.62) LMNAKDM4EGAAL3MBTL1
SCHEMBL29317371 0.78 ESR1 (0.44)
SCHEMBL9680396 0.77 SLC29A1 (0.66) SLC29A1SCN1ASCN2ASCN3ACYP3A4
SCHEMBL23387400 0.77 ESR1 (0.47)
SCHEMBL23914116 0.77 KMT2A (0.63) SLC29A1KMT2AMEN1SMN1; SMN2MAPK1
SCHEMBL22382033 0.77 KMT2A (0.56) KMT2AMEN1HTR2AHTR2BMAPT
SCHEMBL2612557 0.76 SLC29A1 (0.56) SLC29A1SCN1ASCN2ASCN3ACYP3A4
SCHEMBL7406236 0.76 SLC29A1 (0.64) SLC29A1SCN1ASCN2ASCN3ACYP3A4
SCHEMBL7956551 0.76 SLC29A1 (0.64) SLC29A1SCN1ASCN2ASCN3ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD., (JP) 2024-07-18 US disclosed
US-20210317159-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS FUJIMOTO CHEMICALS CO., LTD. (JP) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240239834-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT SLC29A1 148/4885SCN1A 2503/4885SCN2A 3118/4885
US-20210317159-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT SLC29A1 148/4885SCN1A 2503/4885SCN2A 3118/4885
US-20240239833-A1 ALKOXYPHENYL DERIVATIVES, PROTECTED NUCLEOSIDES AND PROTECTED NUCLEOTIDES, METHOD FOR PRODUCING OLIGONUCLEOTIDES, AND METHOD FOR REMOVING SUBSTITUENTS ROS1, POLN, RNMT SLC29A1 148/4885SCN1A 2503/4885SCN2A 3118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.