Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 5/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914584 | 0.92 | XDH (0.34) | XDHIKBKETBK1 | |
| SCHEMBL23915309 | 0.91 | XDH (0.37) | XDHIKBKETBK1 | |
| SCHEMBL23914757 | 0.88 | XDH (0.36) | XDHIKBKETBK1 | |
| SCHEMBL23914673 | 0.88 | SCN9A (0.33) | — | |
| SCHEMBL23914609 | 0.86 | XDH (0.38) | XDHIKBKETBK1 | |
| SCHEMBL23915460 | 0.85 | — | — | |
| SCHEMBL23909131 | 0.84 | XDH (0.36) | XDHIKBKETBK1 | |
| SCHEMBL23914853 | 0.83 | XDH (0.38) | XDHIKBKETBK1 | |
| SCHEMBL23909001 | 0.79 | XDH (0.38) | XDHIKBKETBK1 | |
| SCHEMBL23914589 | 0.78 | SCN9A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | S1PR1, S1PR3, S1PR2 | XDH 3672/4885IKBKE 1543/4885TBK1 2445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.