Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 14/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23914741 | 0.93 | S1PR2 (0.48) | S1PR2 | |
| SCHEMBL23914758 | 0.91 | S1PR2 (0.57) | S1PR2TSHRCMA1PTGDR2ALOX15 | |
| SCHEMBL23914732 | 0.90 | S1PR2 (0.52) | S1PR2 | |
| SCHEMBL23909043 | 0.84 | S1PR2 (0.48) | S1PR2 | |
| SCHEMBL23915377 | 0.83 | S1PR2 (0.37) | S1PR2TSHR | |
| SCHEMBL23966554 | 0.82 | S1PR2 (0.47) | S1PR2 | |
| SCHEMBL23909060 | 0.82 | S1PR2 (0.53) | S1PR2 | |
| SCHEMBL23915555 | 0.76 | — | — | |
| SCHEMBL23908807 | 0.74 | S1PR2 (0.72) | S1PR2TSHRCMA1ALOX15 | |
| SCHEMBL23915376 | 0.74 | S1PR2 (0.37) | S1PR2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | S1PR1, S1PR3, S1PR2 | S1PR2 3/4885TSHR 588/4885CMA1 260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.