Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.48 |
| ▸ | NT5E | P21589 | 17/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20524199 | 1.00 | ADORA1 (0.48) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL21839682 | 0.94 | NT5E (0.48) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL23915647 | 0.94 | NT5E (0.48) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL21839861 | 0.91 | NT5E (0.49) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL30393380 | 0.91 | NT5E (0.49) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL21839659 | 0.90 | NT5E (0.48) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL23915625 | 0.90 | NT5E (0.48) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL30394484 | 0.90 | NT5E (0.48) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL20524289 | 0.90 | NT5E (0.40) | ADORA1ADORA3ADORA2ANT5E | |
| SCHEMBL23914887 | 0.88 | NT5E (0.55) | ADORA1ADORA3ADORA2ANT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | PELOTON THERAPEUTICS INC. (US) | 2023-02-28 | — | — | US | disclosed |
| US-20210317150-A1 | CD73 INHIBITORS AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591355-B2 | CD73 inhibitors and uses thereof | ENTPD5, ENTPD1, ENTPD3 | ADORA1 16/4885ADORA3 9/4885ADORA2A 8/4885 |
| US-20210317150-A1 | CD73 INHIBITORS AND USES THEREOF | ENTPD5, ENTPD1, NT5E | ADORA1 34/4885ADORA3 29/4885ADORA2A 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.