ENTPD3

Ectonucleoside triphosphate diphosphohydrolase 3 · O75355 · ENTPD3 on Sugi Atlas →

986 patent compounds predicted against ENTPD3, 644 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Suramin Suramin (SCHEMBL3161) 1.00 1/20
SCHEMBL12732611 SCHEMBL12732611 1.00 1/20
SCHEMBL13096782 SCHEMBL13096782 1.00 1/20
SCHEMBL13105971 SCHEMBL13105971 1.00 1/20
SCHEMBL21122194 SCHEMBL21122194 1.00 1/20
SCHEMBL21686991 SCHEMBL21686991 0.95 1/20
SCHEMBL20370854 SCHEMBL20370854 0.90 1/20
SCHEMBL16404704 SCHEMBL16404704 0.86 1/20
SCHEMBL3358966 SCHEMBL3358966 0.85 1/20
SCHEMBL22767896 SCHEMBL22767896 0.84 1/20
SCHEMBL16255254 SCHEMBL16255254 0.84 1/20
SCHEMBL16450974 SCHEMBL16450974 0.84 1/20
SCHEMBL11510571 SCHEMBL11510571 0.83 1/20
SCHEMBL11411400 SCHEMBL11411400 0.82 1/20
SCHEMBL20370856 SCHEMBL20370856 0.82 1/20
SCHEMBL11582827 SCHEMBL11582827 0.82 1/20
SCHEMBL11682618 SCHEMBL11682618 0.82 1/20
SCHEMBL375471 SCHEMBL375471 0.80 1/20
SCHEMBL11414391 SCHEMBL11414391 0.80 1/20
SCHEMBL11426198 SCHEMBL11426198 0.80 1/20

Clinical trials — most relevant to ENTPD3 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Daratumumab Intensified Treatment to Eligible MM New Patients CTD-Dara Induction, Follow by Dara Consolidation PHASE3UNKNOWN
Adenosine Signaling Modulation and Immune Checkpoint Inhibition With Hormone Sensitive Oligometastatic Prostate Cancer PHASE2RECRUITING
Clofarabine and Cytarabine in Treating Young Patients With Refractory or Relapsed Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia PHASE1/PHASE2COMPLETED
The Selective Personalized Radio-Immunotherapy for Locally Advanced Non-Small Cell Lung Cancer Trial 2 PHASE2NOT_YET_RECRUITING
A Study of ES002023 (Anti-CD39 Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors PHASE1COMPLETED
A Study of ES014 (Anti-CD39/TGF-β Bispecific Antibody) in Patients With Locally Advanced or Metastatic Solid Tumors PHASE1WITHDRAWN
Vatalanib and Pemetrexed Disodium in Treating Patients With Advanced Solid Tumors PHASE1COMPLETED
A Randomized Controlled Trial of Topical 5% Niacinamide for Skin Cancer Prevention in Transplant Recipients EARLY_PHASE1RECRUITING
Diadenosine Polyphosphates and Mucin Associated With Ocular Surface Disorders nanUNKNOWN
Institution of an Italian Multicenter Database of Patients Affected by Diseases of Phosphate Metabolism nanNOT_YET_RECRUITING
Genetics of Middle Ear Disease nanCOMPLETED
Celiac Disease Genomic Environmental Microbiome and Metabolomic Study nanRECRUITING
PCD New Gene Discovery nanCOMPLETED
CD73+ Th1.17 in Rheumatoid Arthritis and Psoriatic Arthritis nanCOMPLETED
Pathophysiology of Paget's Disease of Bone nanCOMPLETED
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Human Epididymis Protein 4 in Endometrial Carcinoma nanCOMPLETED
Genetics of Primary Ciliary Dyskinesia nanCOMPLETED
Clinical and Genetic Analysis of Enlarged Vestibular Aqueducts nanCOMPLETED
Genetic Feature of Congenital Hearing Loss in Chinese Population nanNOT_YET_RECRUITING
Genetic Risk of Osteonecrosis of the Jaw (ONJ) in Patients With Metastatic Cancer: Concordance Study nanCOMPLETED
Investigate eNAMPT in Multiple Myeloma Biology and Establish Its Role in Disease Progression nanCOMPLETED
Genome Environment Microbiome and Metabolome in Autism Study nanCOMPLETED
A Phase I Trial of AVN944, an IMPDH Inhibitor, in Adults With Advanced Stage Solid Tumors nanWITHDRAWN
Biomarkers to Predict the Response to Pembrolizumab in Chinese NSCLC Patients nanCOMPLETED
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science nanRECRUITING
Protein Expression as a Potential Diagnostic Biomarker of Cervical Dysplasia and/or Cancer nanCOMPLETED
EXtremely Early-onset Type 1 Diabetes EXtremely Early-onset Type 1 Diabetes (A Musketeers' Memorandum Study) nanRECRUITING
miRNAs Profiling in Parkinson's Disease nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a ENTPD3 binder may also engage these)

ProteinNameSimilarity
P79784 0.995 P79784 →
Q8BFW6 0.994 Q8BFW6 →
P97687 0.990 P97687 →
Q9MYU4 0.989 Q9MYU4 →
O18956 0.983 O18956 →
P55772 0.979 P55772 →
E1BPW0 0.978 E1BPW0 →
ENTPD5 Nucleoside diphosphate phosphatase ENTPD5 0.973 landscape →
O93295 0.972 O93295 →
D2GZV9 0.972 D2GZV9 →
Q8K0L2 0.971 Q8K0L2 →
Q617Y0 0.971 Q617Y0 →
Q28CF8 0.971 Q28CF8 →
Q21815 0.970 Q21815 →
Q2M3T9 0.970 Q2M3T9 →
Q6AYF4 0.969 Q6AYF4 →
P97278 0.969 P97278 →
Q9QYC8 0.969 Q9QYC8 →
Q6DYE8 0.969 Q6DYE8 →
Q05A56 0.969 Q05A56 →
A2A863 0.968 A2A863 →
Q1RPR6 0.968 Q1RPR6 →
Q6T3U3 0.968 Q6T3U3 →
Q641Z7 0.968 Q641Z7 →
Q5R748 0.968 Q5R748 →
Q5DRK1 0.968 Q5DRK1 →
Q29052 0.968 Q29052 →
Q9UHG3 0.968 Q9UHG3 →
O95498 0.967 O95498 →
P43406 0.967 P43406 →