Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909127 | 0.86 | NPC1 (0.43) | S1PR2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23966503 | 0.85 | S1PR2 (0.36) | S1PR2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23914498 | 0.80 | KDM4E (0.41) | S1PR2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23914832 | 0.80 | ALDH1A1 (0.36) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL23914597 | 0.79 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDLMNAHTT | |
| SCHEMBL23914657 | 0.78 | SMN1; SMN2 (0.36) | S1PR2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23914840 | 0.78 | S1PR2 (0.38) | S1PR2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23914490 | 0.78 | MAPT (0.44) | S1PR2KMT2ATSHRSLC16A3HSD17B10 | |
| SCHEMBL23915526 | 0.77 | S1PR2 (0.46) | S1PR2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL23914489 | 0.76 | SLC16A3 (0.33) | ALDH1A1KDM4EHPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | GILEAD SCIENCES, INC. | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210315893-A1 | NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS | S1PR1, S1PR3, S1PR2 | S1PR2 3/4885ALDH1A1 944/4885KDM4E 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.