Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 2/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23916715 | 1.00 | HRH3 (0.51) | HRH3HSD17B10ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL23048856 | 0.84 | HRH3 (0.53) | HRH3HSD17B10ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL23916158 | 0.77 | HRH4 (0.54) | HRH3HSD17B10ALDH1A1CYP2D6HPGD | |
| SCHEMBL23916096 | 0.77 | HRH4 (0.54) | HRH3HSD17B10ALDH1A1CYP2D6HPGD | |
| Hydrochloric Acid SCHEMBL30327773 | 0.72 | ADRB1 (0.66) | HRH3HSD17B10ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL23048818 | 0.70 | DYRK1A (0.42) | HSD17B10ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL23048624 | 0.68 | DYRK1A (0.39) | HRH3HSD17B10ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL2166795 | 0.68 | HRH3 (1.00) | HRH3HSD17B10ALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL25147566 | 0.68 | CYP3A4 (0.49) | HRH3HSD17B10ALDH1A1CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL3786113 | 0.67 | HRH3 (0.97) | HRH3HSD17B10ALDH1A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892276-A1 | ISOQUINOLIN-3-YL CARBOXAMIDES AS WNT INHIBITORS | BioSplice Therapeutics, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |