Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PDE6D | O43924 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917158 | 0.76 | KDM4E (0.45) | HPGDALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL23917164 | 0.72 | PTGER4 (0.45) | HPGDALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL23917125 | 0.70 | HPGD (0.48) | HPGDALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL21364427 | 0.69 | ALDH1A1 (0.47) | HPGDALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL16436819 | 0.69 | ESR1 (0.56) | HPGDALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL16436818 | 0.68 | ESR1 (0.51) | HPGDALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL23917152 | 0.67 | HSD17B10 (0.41) | HPGDALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL18999329 | 0.65 | ESR2 (0.58) | HPGDALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL23169736 | 0.65 | ESR1 (0.54) | HPGDALDH1A1KDM4EKMT2APOLB | |
| SCHEMBL23169648 | 0.65 | ESR1 (0.50) | HPGDALDH1A1KDM4EKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-02-14 | — | — | US | disclosed |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | HPGD 1534/4885ALDH1A1 504/4885KDM4E 2132/4885 |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | HPGD 1534/4885ALDH1A1 504/4885KDM4E 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.