Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.56 |
| ▸ | BTK | Q06187 | 3/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.31 |
| ▸ | PRKDC | P78527 | 2/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | HCK | P08631 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20093476 | 0.74 | VRK1 (0.41) | PIK3CDBTKEGFRPIK3CAPIK3CB | |
| SCHEMBL11975 | 0.73 | PIK3CB (0.39) | PIK3CDBTKEGFRPIK3CAPIK3CB | |
| SCHEMBL23917192 | 0.73 | MAP4K4 (0.38) | PIK3CDBTKEGFRPIK3CAPIK3CB | |
| SCHEMBL16655566 | 0.72 | PIK3CD (1.00) | PIK3CDBTK | |
| SCHEMBL16655157 | 0.71 | PIK3CD (0.47) | PIK3CDBTKEGFRPIK3CAPIK3CB | |
| SCHEMBL9010 | 0.69 | PIK3CG (0.54) | PIK3CDBTKEGFRPIK3CAPIK3CB | |
| SCHEMBL21245727 | 0.68 | CDK4 (0.53) | PIK3CDBTKCDK4CDK6EGFR | |
| SCHEMBL13718282 | 0.68 | PDE3B (0.44) | — | |
| SCHEMBL21467056 | 0.68 | PIK3CD (0.55) | PIK3CDEGFRPIK3CAPIK3CBPIK3CG | |
| SCHEMBL16065725 | 0.67 | PIK3CD (0.53) | PIK3CDBTKEGFRPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | PIK3CD 2/4885BTK 1/4885CDK4 164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.