Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 10/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | GLA | P06280 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | USP7 | Q93009 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917331 | 0.85 | ALDH1A1 (0.47) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917126 | 0.83 | KDM4E (0.45) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917366 | 0.83 | ALDH1A1 (0.42) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917357 | 0.82 | KDM4E (0.48) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917329 | 0.79 | KDM4E (0.45) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917372 | 0.78 | ALDH1A1 (0.42) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917075 | 0.74 | KDM4E (0.45) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL21622976 | 0.73 | KDM4E (0.51) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL23917332 | 0.71 | KDM4E (0.47) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL21622883 | 0.71 | KDM4E (0.47) | GAAKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-02-14 | — | — | US | disclosed |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11581497-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | GAA 2390/4885KDM4E 2132/4885ALDH1A1 504/4885 |
| US-20210320264-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | OR10J3, EPCAM, L1CAM | GAA 2390/4885KDM4E 2132/4885ALDH1A1 504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.