⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4393999 | 0.78 | ALDH1A1 (0.33) | — | |
| SCHEMBL18898876 | 0.74 | TSHR (0.30) | — | |
| SCHEMBL2497744 | 0.73 | — | — | |
| SCHEMBL4120760 | 0.71 | TSHR (0.33) | — | |
| SCHEMBL8243889 | 0.69 | — | — | |
| SCHEMBL2496094 | 0.69 | — | — | |
| SCHEMBL20180563 | 0.68 | — | — | |
| SCHEMBL16233072 | 0.67 | CHRM2 (0.40) | — | |
| SCHEMBL2497211 | 0.66 | — | — | |
| SCHEMBL12092222 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11584801-B2 | Anti-5T4 antibodies and antibody-drug conjugates | BYONDIS B.V. (NL) | 2023-02-21 | — | — | US | disclosed |
| US-20210317231-A1 | ANTI-5T4 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES | BYONDIS BV (NL) | 2021-10-14 | — | — | US | disclosed |