SCHEMBL23917358

SCHEMBL23917358

c1ccc(-c2nc(-n3c4ccccc4c4c3ccc3nc5ccccn5c34)c3ccccc3n2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP1 P24666 2/20 0.41
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 2/20 0.40
GLA P06280 2/20 0.40
GAA P10253 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
ABCG2 Q9UNQ0 3/20 0.39
PDE5A O76074 1/20 0.38
TSHR P16473 3/20 0.37
HSD17B10 Q99714 3/20 0.37
MAPK1 P28482 1/20 0.37
LMNA P02545 5/20 0.36
ACHE P22303 1/20 0.36
MEN1 O00255 2/20 0.36
USP2 O75604 2/20 0.36
KMT2A Q03164 2/20 0.36
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
HIF1A Q16665 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23917077 0.88 KDM4E (0.40) ACP1KDM4EALDH1A1GLAGAA
SCHEMBL23917102 0.80 ALDH1A1 (0.42) KDM4EALDH1A1GLAGAASMN1; SMN2
SCHEMBL23917290 0.78 ACP1 (0.41) ACP1KDM4EALDH1A1GLAGAA
SCHEMBL20226347 0.78 ACP1 (0.49) ACP1KDM4EALDH1A1ABCG2TSHR
SCHEMBL15213847 0.78 ACP1 (0.49) ACP1KDM4EALDH1A1SMN1; SMN2ABCG2
SCHEMBL13877271 0.77 ACP1 (0.59) ACP1KDM4EALDH1A1ABCG2PDE5A
SCHEMBL23917374 0.76 KDM4E (0.37) KDM4EALDH1A1GLAGAASMN1; SMN2
SCHEMBL20226345 0.76 ACP1 (0.47) ACP1KDM4EALDH1A1SMN1; SMN2ABCG2
SCHEMBL23917312 0.75 KDM4E (0.41) KDM4EALDH1A1GLAGAASMN1; SMN2
SCHEMBL23917409 0.75 KDM4E (0.34) KDM4EALDH1A1GLAGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11581497-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2023-02-14 US disclosed
EP-3820966-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-06-08 EP disclosed
US-20210320264-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11581497-B2 Materials for organic electroluminescent devices OR10J3, EPCAM, L1CAM ACP1 4128/4885KDM4E 2132/4885ALDH1A1 504/4885
US-20210320264-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM ACP1 4128/4885KDM4E 2132/4885ALDH1A1 504/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.