Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | BTK | Q06187 | 1/20 | 0.53 |
| ▸ | TNK2 | Q07912 | 16/20 | 0.53 |
| ▸ | IGF1R | P08069 | 3/20 | 0.46 |
| ▸ | INSR | P06213 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16665719 | 0.86 | PIK3CD (0.53) | PIK3CDBTKTNK2IGF1RINSR | |
| SCHEMBL16655780 | 0.82 | TNK2 (0.55) | PIK3CDBTKTNK2IGF1R | |
| SCHEMBL16655468 | 0.81 | ACVRL1 (0.53) | PIK3CDBTK | |
| SCHEMBL16665715 | 0.80 | PIK3CD (0.54) | PIK3CDBTKTNK2IGF1R | |
| SCHEMBL16665724 | 0.77 | TNK2 (0.53) | TNK2IGF1RINSR | |
| SCHEMBL16665725 | 0.72 | PIK3CD (0.55) | PIK3CDBTKTNK2IGF1R | |
| SCHEMBL16665716 | 0.71 | PIK3CD (0.51) | PIK3CDBTKTNK2IGF1R | |
| SCHEMBL8240001 | 0.69 | TNK2 (0.83) | TNK2IGF1R | |
| SCHEMBL16655677 | 0.69 | PIK3CD (1.00) | PIK3CDBTK | |
| SCHEMBL4353507 | 0.69 | TNK2 (1.00) | TNK2IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | PIK3CD 2/4885BTK 1/4885TNK2 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.