Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 11/20 | 0.43 |
| ▸ | BTK | Q06187 | 11/20 | 0.43 |
| ▸ | ATR | Q13535 | 6/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655487 | 0.75 | PIK3CD (0.52) | PIK3CDBTKATR | |
| SCHEMBL16655203 | 0.73 | PIK3CD (0.73) | PIK3CDBTKATR | |
| SCHEMBL16655376 | 0.69 | PIK3CD (0.46) | PIK3CDBTKATR | |
| SCHEMBL24429536 | 0.66 | RET (0.31) | PIK3CD | |
| SCHEMBL30321052 | 0.66 | RET (0.39) | PIK3CDCDK2 | |
| SCHEMBL24096859 | 0.66 | NR3C1 (0.39) | — | |
| SCHEMBL24096857 | 0.66 | RET (0.39) | PIK3CDCDK2 | |
| SCHEMBL20645214 | 0.63 | ESR1 (0.36) | PIK3CD | |
| SCHEMBL16655916 | 0.62 | PIK3CD (0.74) | PIK3CDBTKATR | |
| SCHEMBL22902484 | 0.60 | BTK (0.55) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | MEDIVATION TECHNOLOGIES, INC. (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317140-A1 | Heterocyclic Compounds and Methods of Use | BTK, PIK3CD, PIK3CB | PIK3CD 2/4885BTK 1/4885ATR 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.