Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM1A | O60341 | 2/20 | 0.59 |
| ▸ | MAOA | P21397 | 2/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.58 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582508 | 0.90 | POLB (0.58) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL15623097 | 0.88 | MEN1 (0.55) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL592715 | 0.88 | POLB (0.66) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL1755631 | 0.88 | MEN1 (0.55) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL10598558 | 0.87 | POLB (0.69) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL10595799 | 0.87 | POLB (0.73) | ALDH1A1POLBTP53MAPTRAB9A | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.87 | POLB (0.78) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL1163051 | 0.87 | GAA (0.66) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL16329499 | 0.86 | MEN1 (0.53) | ALDH1A1POLBTP53MAPTRAB9A | |
| SCHEMBL1160238 | 0.86 | POLB (0.64) | ALDH1A1POLBTP53MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892305-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | Sutro Biopharma, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |