Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.53 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23917849 | 0.90 | ALDH1A1 (0.69) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL590420 | 0.85 | POLB (0.62) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL8405338 | 0.83 | POLB (0.54) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL3968088 | 0.83 | POLB (0.64) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL8867533 | 0.83 | POLB (0.64) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL19089782 | 0.83 | POLB (0.57) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL8550190 | 0.82 | POLB (0.53) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL21054940 | 0.82 | POLB (0.62) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL19682897 | 0.82 | POLB (0.62) | POLBNPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL592715 | 0.81 | POLB (0.66) | POLBNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | KATO KANEYOSHI | 2007-07-26 | — | — | US | disclosed |
| US-7115750-B1 | Melanin concentrating hormone antagonist | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173498-A1 | Melanin concentrating hormone antagonist | MC1R, MCHR1, MCHR2 | POLB 4114/4885NPC1 1085/4885RAB9A 1813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.