Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 5/20 | 0.32 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21503844 | 0.91 | NPY4R (0.36) | FURINSIRT5 | |
| SCHEMBL24349699 | 0.87 | SIRT5 (0.36) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL22139609 | 0.87 | SIRT5 (0.36) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL22692383 | 0.85 | C3AR1 (0.34) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL24173258 | 0.85 | C3AR1 (0.34) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL21914949 | 0.85 | C3AR1 (0.34) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL23126444 | 0.85 | FURIN (0.38) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL22198634 | 0.85 | C3AR1 (0.34) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL20803561 | 0.85 | C3AR1 (0.34) | FURINC3AR1SIRT5SIRT6SIRT1 | |
| SCHEMBL21788282 | 0.85 | FURIN (0.38) | FURINC3AR1SIRT5SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892305-A1 | HEMIASTERLIN DERIVATIVES FOR CONJUGATION AND THERAPY | Sutro Biopharma, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |