SCHEMBL23918186

SCHEMBL23918186

CC(Cc1ccc(SF)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 4/20 0.45
KMT2A Q03164 2/20 0.45
PTPN1 P18031 1/20 0.42
EPHX2 P34913 1/20 0.42
PIN1 Q13526 1/20 0.41
MDM4 O15151 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30704249 0.87 CASP3 (0.54) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL19622257 0.87 CASP3 (0.54) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL2949021 0.84 CASP3 (0.49) CASP3KMT2APTPN1EPHX2MDM4
SCHEMBL11948879 0.80 CASP3 (0.49) CASP3KMT2AEPHX2MDM4TP53
SCHEMBL13624662 0.79 CASP3 (0.41) CASP3KMT2APTPN1PIN1
SCHEMBL31105156 0.79 PTPN1 (0.45) CASP3KMT2APTPN1EPHX2
SCHEMBL31520526 0.79 KMT2A (0.54) CASP3KMT2AEPHX2PIN1MDM4
SCHEMBL12714718 0.79 KMT2A (0.54) CASP3KMT2AEPHX2PIN1MDM4
SCHEMBL29400279 0.79 KMT2A (0.54) CASP3KMT2AEPHX2PIN1MDM4
SCHEMBL29401663 0.79 KMT2A (0.54) CASP3KMT2AEPHX2PIN1MDM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892610-A1 SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE AS SCREENING AGENT The Scripps Research Institute (US) 2021-10-13 EP disclosed