Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GSR | P00390 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24238129 | 0.82 | MEN1 (0.65) | LMNAGSRALDH1A1HSD17B10KDM4E | |
| SCHEMBL29376359 | 0.82 | MEN1 (0.65) | LMNAGSRALDH1A1HSD17B10KDM4E | |
| SCHEMBL9635970 | 0.81 | HTT (0.54) | GSRALDH1A1KDM4ETSHRHTT | |
| SCHEMBL12287205 | 0.80 | GSR (0.51) | LMNAGSRALDH1A1HSD17B10KDM4E | |
| SCHEMBL28727266 | 0.80 | TLR8 (0.54) | GSRALDH1A1HSD17B10KDM4EHTT | |
| SCHEMBL28834402 | 0.79 | GFER (0.53) | LMNAGSRALDH1A1HSD17B10KDM4E | |
| SCHEMBL9637273 | 0.79 | ALDH1A1 (0.62) | LMNAGSRALDH1A1KDM4ETSHR | |
| SCHEMBL11307165 | 0.79 | GSR (0.55) | LMNAGSRALDH1A1HSD17B10KDM4E | |
| SCHEMBL864092 | 0.77 | GSR (0.48) | LMNAGSRALDH1A1HSD17B10KDM4E | |
| SCHEMBL3476023 | 0.76 | GSR (0.65) | GSRALDH1A1HSD17B10KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210317157-A1 | Substituted Alloxazine Nucleosides and Nucleotides, and Methods of Making Same | UNIV COLORADO REGENTS (US) | 2021-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210317157-A1 | Substituted Alloxazine Nucleosides and Nucleotides, and Methods of Making Same | NT5C2, PNP, SLC35B2 | LMNA 1590/4885GSR 1578/4885ALDH1A1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.