SCHEMBL23918215

SCHEMBL23918215

Clc1ccc2c(c1)Oc1ccc(N(c3ccccc3)c3ccccc3)cc1S2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.40
BCHE P06276 2/20 0.35
ACHE P22303 2/20 0.35
NOX1 Q9Y5S8 1/20 0.35
TDP1 Q9NUW8 3/20 0.32
LMNA P02545 3/20 0.32
CYP3A4 P08684 3/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2D6 P10635 2/20 0.32
CYP2C19 P33261 2/20 0.32
SLC22A1 O15245 1/20 0.32
MLNR O43193 1/20 0.32
NR1I2 O75469 1/20 0.32
ABCB11 O95342 1/20 0.32
CHRM2 P08172 1/20 0.32
ADRB1 P08588 1/20 0.32
HTR1A P08908 1/20 0.32
ADRA2A P08913 1/20 0.32
ADORA3 P0DMS8 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22180416 0.94 AHR (0.36) AHRBCHEACHENOX1TDP1
SCHEMBL22180408 0.94 AHR (0.35) AHRBCHEACHENOX1
SCHEMBL23918218 0.90 BCHE (0.37) AHRBCHEACHENOX1TDP1
SCHEMBL22180139 0.89 AHR (0.32) AHR
SCHEMBL22180410 0.88 KDM4E (0.37) AHRKDM4E
SCHEMBL22180138 0.86 AHR (0.36) AHRBCHEACHENOX1TDP1
SCHEMBL23918019 0.85 TDP1 (0.30) TDP1LMNACYP3A4CYP1A2CYP2D6
SCHEMBL23918219 0.81 AHR (0.59) AHRTDP1CYP3A4CYP1A2CYP2D6
SCHEMBL23918224 0.81 BCHE (0.41) BCHEACHENOX1TDP1LMNA
SCHEMBL22180134 0.81 BCHE (0.41) BCHEACHENOX1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320258-A1 COMPOUND FOR AN ORGANIC ELECTRIC ELEMENT, AN ORGANIC ELECTRIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2021-10-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320258-A1 COMPOUND FOR AN ORGANIC ELECTRIC ELEMENT, AN ORGANIC ELECTRIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF PIEZO1, OR10J3, OCIAD1 AHR 4105/4885BCHE 1769/4885ACHE 491/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.