SCHEMBL23918358

SCHEMBL23918358

Cc1nc2c(cnn2C2CCC(F)(F)CC2)c(=O)[nH]1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PDE9A O76083 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22042919 0.86 PDE9A (0.62) PDE9A
SCHEMBL6338426 0.83 PDE9A (0.65) PDE9A
SCHEMBL6338713 0.83 PDE9A (0.59) PDE9A
SCHEMBL22072365 0.83 PDE9A (0.57) PDE9A
SCHEMBL6898925 0.83 PDE9A (0.67) PDE9A
SCHEMBL22071807 0.83 PDE9A (0.56) PDE9A
SCHEMBL6369064 0.82 PDE9A (0.71) PDE9A
SCHEMBL6339510 0.82 PDE9A (0.71) PDE9A
SCHEMBL6339076 0.82 PDE9A (0.57) PDE9A
SCHEMBL14771558 0.82 PDE9A (0.66) PDE9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3892622-A1 COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF Korea Research Institute of Chemical Technology (KR) 2021-10-13 EP disclosed