Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 19/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22072396 | 0.90 | LMNA (0.57) | PDE9ALMNAESR1L3MBTL1 | |
| SCHEMBL22072398 | 0.86 | PDE9A (0.61) | PDE9ALMNAESR1L3MBTL1 | |
| SCHEMBL22071796 | 0.86 | PDE9A (0.53) | PDE9A | |
| SCHEMBL22072365 | 0.86 | PDE9A (0.57) | PDE9AL3MBTL1 | |
| SCHEMBL22072389 | 0.85 | CYP1A2 (0.58) | PDE9A | |
| SCHEMBL22071810 | 0.84 | LMNA (0.52) | PDE9ALMNAESR1L3MBTL1 | |
| SCHEMBL6338713 | 0.83 | PDE9A (0.59) | PDE9A | |
| SCHEMBL22072283 | 0.83 | PDE9A (0.53) | PDE9A | |
| SCHEMBL22072361 | 0.83 | PDE9A (0.55) | PDE9A | |
| SCHEMBL23918358 | 0.83 | PDE9A (0.67) | PDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020116972-A1 | COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF | 한국화학연구원 | 2020-06-11 | — | — | WO | disclosed |