Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7999668 | 0.77 | CYP19A1 (0.42) | RECQLSMN1; SMN2KMT2AKDM4EALDH1A1 | |
| SCHEMBL10556483 | 0.69 | GAA (0.33) | NPSR1SMN1; SMN2TSHRKMT2AALDH1A1 | |
| SCHEMBL16691744 | 0.66 | NPSR1 (0.40) | RECQLNPSR1HSP90AA1CCR6SMN1; SMN2 | |
| SCHEMBL18570204 | 0.66 | RECQL (0.61) | RECQLNPSR1HSP90AA1CCR6SMN1; SMN2 | |
| SCHEMBL14450568 | 0.66 | HTT (0.55) | RECQLNPSR1HSP90AA1CCR6SMN1; SMN2 | |
| SCHEMBL9123388 | 0.65 | — | — | |
| SCHEMBL29332053 | 0.63 | HSP90AA1 (0.43) | RECQLNPSR1HSP90AA1CCR6KMT2A | |
| SCHEMBL11090825 | 0.60 | RECQL (0.44) | RECQLNPSR1HSP90AA1CCR6SMN1; SMN2 | |
| SCHEMBL21784224 | 0.60 | HTT (0.49) | RECQLNPSR1HSP90AA1CCR6SMN1; SMN2 | |
| SCHEMBL12567851 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892734-A1 | SCREENING METHODS AND THERAPEUTIC APPLICATIONS BASED ON BACTERIAL MOTILITY INHIBITION | Ludwig-Maximilians-Universität München (DE) | 2021-10-13 | — | — | EP | disclosed |