Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 8/20 | 0.46 |
| ▸ | NR0B2 | Q15466 | 3/20 | 0.46 |
| ▸ | RARB | P10826 | 5/20 | 0.42 |
| ▸ | RARA | P10276 | 5/20 | 0.41 |
| ▸ | RARG | P13631 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTPRCAP | Q14761 | 2/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393703 | 0.92 | PTPN11 (0.49) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2390953 | 0.86 | PSEN1 (0.37) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2404992 | 0.86 | PTPN11 (0.58) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2404988 | 0.86 | PTPN11 (0.58) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2391835 | 0.83 | PTPN11 (0.48) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2391145 | 0.81 | RARB (0.51) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2391149 | 0.81 | RARB (0.51) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2393218 | 0.80 | S1PR1 (0.41) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2391094 | 0.78 | PTPN11 (0.68) | PTPN11NR0B2RARBRARARARG | |
| SCHEMBL2391808 | 0.78 | PTPN11 (0.54) | PTPN11NR0B2RARBRARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |