Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | RARA | P10276 | 3/20 | 0.39 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RARG | P13631 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.39 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2390953 | 0.94 | PSEN1 (0.37) | S1PR1LMNARARARARBRARG | |
| SCHEMBL6022901 | 0.87 | HDAC11 (0.47) | S1PR1LMNARARARARBRARG | |
| SCHEMBL6022897 | 0.87 | HDAC11 (0.47) | S1PR1LMNARARARARBRARG | |
| SCHEMBL2393703 | 0.85 | PTPN11 (0.49) | LMNARARARARBRARGMEN1 | |
| SCHEMBL2387856 | 0.85 | RARA (0.49) | S1PR1LMNARARARARBRARG | |
| SCHEMBL2390735 | 0.85 | HDAC11 (0.40) | S1PR1LMNARARARARBRARG | |
| SCHEMBL2391184 | 0.85 | PSEN1 (0.42) | S1PR1LMNARARARARBRARG | |
| SCHEMBL2391841 | 0.85 | HDAC11 (0.42) | S1PR1LMNARARARARBRARG | |
| SCHEMBL2395834 | 0.84 | PTPN11 (0.48) | S1PR1LMNARARARARBRARG | |
| SCHEMBL2394296 | 0.83 | HDAC11 (0.45) | S1PR1LMNARARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE42700-E1 | Induction of apoptosis in cancer cells | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2011-09-13 | — | — | US | disclosed |