SCHEMBL23918685

SCHEMBL23918685

COc1ccc(N2CN2c2ccc(OC)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA12 O43570 1/20 0.55
CA14 Q9ULX7 1/20 0.55
POLB P06746 1/20 0.52
HTR3E A5X5Y0 1/20 0.50
HTR3B O95264 1/20 0.50
ADRB1 P08588 1/20 0.50
HTR3A P46098 1/20 0.50
HTR3D Q70Z44 1/20 0.50
HTR3C Q8WXA8 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
MGLL Q99685 1/20 0.48
ACHE P22303 1/20 0.46
HTT P42858 1/20 0.45
KMT2A Q03164 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11504114 0.80 HTR3E (0.61) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL21802643 0.74 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.74 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL4793606 0.73 HTR3E (0.59) CA1CA2CA7CA9CA12
SCHEMBL14873719 0.72 CA1 (0.58) CA1CA2CA7CA9CA12
SCHEMBL16789887 0.71 HTR3E (0.52) CA1CA2CA7CA9CA12
SCHEMBL2925759 0.71 HTR3E (0.68) POLBHTR3EHTR3BADRB1HTR3A
SCHEMBL16592412 0.71 CA1 (0.50) CA1CA2CA7CA9CA12
SCHEMBL15993007 0.70 POLB (0.43) CA1CA2CA7CA9CA12
SCHEMBL20415006 0.70 HTR3E (0.66) POLBHTR3EHTR3BADRB1HTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210318231-A1 Liquid Crystal-Based Detection of Air Contaminants Using Metal Surfaces NATIONAL SCIENCE FOUNDATION 2021-10-14 US disclosed