Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16559829 | 0.86 | POLB (0.47) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16559838 | 0.85 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL24440871 | 0.84 | POLB (0.43) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL16573122 | 0.84 | POLB (0.49) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19804174 | 0.83 | POLB (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL22219319 | 0.82 | ELANE (0.42) | ELANEPTPN11TSHRKMT2AATM | |
| SCHEMBL16559812 | 0.82 | POLB (0.44) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL23643282 | 0.82 | POLB (0.42) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL19804340 | 0.82 | POLB (0.47) | POLBAPEX1HTTTDP1PTPN11 | |
| SCHEMBL18308843 | 0.81 | POLB (0.56) | POLBAPEX1HTTTDP1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892706-A2 | LIQUID-CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2021-10-13 | — | — | EP | disclosed |